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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFIC All Species: 19.39
Human Site: S477 Identified Species: 53.33
UniProt: P08651 Number Species: 8
    Phosphosite Substitution
    Charge Score: -0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08651 NP_005588.2 508 55675 S477 S P T S P S Y S P P D T S P A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001117899 1094 117090 S861 S P T S P S Y S P P D T S P A
Dog Lupus familis XP_542179 569 62116 S538 S P T S P S Y S T P G T S P A
Cat Felis silvestris
Mouse Mus musculus P70255 439 48750 L409 P Q D P L K D L V S L A C D P
Rat Rattus norvegicus P09414 509 55958 S476 S P T S P T Y S T P S T S P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507360 560 62601 R472 S G T S Q A N R Y V G L S P R
Chicken Gallus gallus P17926 439 49214 L409 P Q D P L K D L V S L A C D P
Frog Xenopus laevis NP_001089972 501 55469 S470 S P T S P T Y S A P S T P P T
Zebra Danio Brachydanio rerio XP_001921162 553 61079 S497 S P T S P T Y S A P G T P P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 46 86.9 N.A. 82.4 65.2 N.A. 54.4 79.3 81.8 75.9 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 46.2 87.8 N.A. 84.4 75.4 N.A. 65 82.6 90.1 83.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 86.6 N.A. 0 80 N.A. 33.3 0 66.6 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 86.6 N.A. 0 86.6 N.A. 40 0 73.3 80 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 12 0 0 23 0 0 23 0 0 56 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 23 0 0 % C
% Asp: 0 0 23 0 0 0 23 0 0 0 23 0 0 23 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 12 0 0 0 0 0 0 0 0 34 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 23 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 23 0 0 23 0 0 23 12 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 0 % N
% Pro: 23 67 0 23 67 0 0 0 23 67 0 0 23 78 23 % P
% Gln: 0 23 0 0 12 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 12 % R
% Ser: 78 0 0 78 0 34 0 67 0 23 23 0 56 0 0 % S
% Thr: 0 0 78 0 0 34 0 0 23 0 0 67 0 0 12 % T
% Val: 0 0 0 0 0 0 0 0 23 12 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 67 0 12 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _